Drug intelligence / Profile preview

cefixime + potassium clavulanate

Development stage
Unknown
Lead developer
Grevis Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Gremax-CV is an oral combination antibiotic containing cefixime, a third-generation cephalosporin, and potassium clavulanate, a beta-lactamase inhibitor. Cefixime works by binding to penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis, leading to cell lysis and death. Potassium clavulanate acts as a suicide inhibitor of bacterial beta-lactamase enzymes, protecting cefixime from enzymatic degradation and overcoming bacterial resistance. Developed by Grevis Pharma, Gremax-CV is formulated as a tablet and is indicated for the treatment of various bacterial infections, including urinary tract infections, otitis media, pharyngitis, tonsillitis, and uncomplicated gonorrhea.

Brand names
Gremax CVGremax-CV
Other names
cefixime + clavulanic acidcefixime and clavulanic acidcefixime and potassium clavulanatecefixime clavulanatecefixime potassium clavulanate
02

Targets

PBP (Penicillin-binding protein family)Neuraminidaseβ-lactamase

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