cephalexin + metronidazole

Cephalexin + metronidazole is a combination of two antibiotics used together to treat mixed bacterial infections, particularly those involving both aerobic and anaerobic bacteria. Cephalexin is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, primarily targeting gram-positive organisms. Metronidazole is a nitroimidazole antibiotic effective against anaerobic bacteria and certain protozoa; it works by disrupting DNA synthesis in susceptible organisms. This combination may be used empirically for polymicrobial infections such as intra-abdominal or pelvic infections where both aerobic and anaerobic pathogens are suspected[4][5][6]. The drugs act via distinct mechanisms, providing broad-spectrum antibacterial coverage.