cerebraca wafer + temozolomide

Cerebraca Wafer + temozolomide is a combination therapy designed for the treatment of brain tumors, particularly high-grade gliomas and glioblastoma. **Cerebraca Wafer** is an implantable local drug delivery system that releases its active pharmaceutical ingredient (commonly targeting cell proliferation and survival pathways) directly into the tumor resection cavity post-surgery, aiming to maximize local antitumor effect and minimize systemic toxicity. **Temozolomide** is an oral alkylating chemotherapy agent that works by methylating DNA, leading to tumor cell death, and is standard-of-care in combination with radiation and/or other modalities for glioblastoma and other high-grade brain tumors. This combination aims to synergize local (wafer-based) and systemic (oral) chemotherapeutic effects to improve progression-free and overall survival for patients with malignant brain tumors. The primary indication is for high-grade gliomas, including glioblastoma multiforme.

Other names

tmz