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CG3001 (Renji Hospital)

Development stage: Unknown
Lead developer: Renji Hospital
Modality: CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Administration: Intravenous

Overview

CG3001 is an autologous chimeric antigen receptor (CAR) T-cell therapy developed by RenJi Hospital for the treatment of CD19-positive B-cell malignancies. The therapy involves the genetic modification of a patient's own T cells using a lentiviral vector to express a CAR specific for the CD19 antigen. Once re-infused into the patient, these redirected T cells recognize and eliminate CD19-expressing malignant B cells. CG3001 is primarily indicated for B-cell leukemia and B-cell lymphoma and is currently undergoing Phase 1 clinical evaluation to assess its safety, tolerability, and engraftment levels.

Other names: CAR-CD19 T cellsCAR-CD-19 T cellsCAR-CD 19 T cellsanti-CD19 CAR-T cellsanti-CD-19 CAR-T cellsanti-CD 19 CAR-T cellsAutologous anti-CD19 CAR-T cells

Targets

CD19 (B lymphocyte antigen CD19)

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