Chang'an No. 1 Formula

Chang'an No. 1 Formula (中药肠安Ⅰ号方) is a traditional Chinese medicine (TCM) herbal compound designed for the treatment of gastrointestinal disorders, particularly those involving intestinal inflammation and mucosal barrier dysfunction such as irritable bowel syndrome (IBS). While direct published data on "Chang'an No. 1" is limited in English-language sources, it appears to be part of a series of TCM formulas targeting gut health; related formulas like "Chang’an II" have demonstrated anti-inflammatory and immunomodulatory effects in preclinical models by repairing the intestinal mucosal barrier and modulating immune cell ratios and cytokine expression[2]. The mechanism of action is believed to involve multiple herbal components acting synergistically to reduce inflammation, restore immune balance in the gut mucosa (e.g., normalizing CD4+/CD8+ T-cell ratios), decrease pro-inflammatory cytokines such as IL-1β while increasing anti-inflammatory cytokines like IL-4[2]. The formula likely follows classical TCM principles for harmonizing liver and spleen function according to syndrome differentiation.

Brand names

Chang'an No. 1 Formula中药肠安Ⅰ号方

Other names

Chang'an IChangan I formula肠安一号方