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Changji'an Capsule
- Development stage
- Phase 3
- Lead developer
- First Affiliated Hospital of Guangzhou University of Chinese Medicine
- Administration
- Oral
01
Overview
Changji'an Capsule is a Traditional Chinese Medicine (TCM) formulation developed by The First Affiliated Hospital of Guangzhou University of Chinese Medicine. It is primarily investigated for the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D), specifically targeting the "Liver Qi invading Spleen" syndrome (Gan Yu Cheng Pi). The formulation is designed to harmonize the liver and spleen, a common therapeutic approach in TCM for gastrointestinal disorders characterized by abdominal pain and altered bowel habits. Clinical evaluation has focused on its efficacy in reducing abdominal pain and improving stool consistency in IBS-D patients.
- Brand names
- Chang-Ji-AnChangji'an capsule
- Other names
- Changji'an CapsuleChangji'an Jiaonang
02
Targets
NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)NGF (Nerve growth factor)NTRK1 (Tropomyosin-related receptor kinase A)NF-κBTNFA (Tumor necrosis factor alpha (soluble))
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