Drug intelligence / Profile preview

Changji'an Capsule

Development stage
Phase 3
Lead developer
First Affiliated Hospital of Guangzhou University of Chinese Medicine
Administration
Oral
01

Overview

Changji'an Capsule is a Traditional Chinese Medicine (TCM) formulation developed by The First Affiliated Hospital of Guangzhou University of Chinese Medicine. It is primarily investigated for the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D), specifically targeting the "Liver Qi invading Spleen" syndrome (Gan Yu Cheng Pi). The formulation is designed to harmonize the liver and spleen, a common therapeutic approach in TCM for gastrointestinal disorders characterized by abdominal pain and altered bowel habits. Clinical evaluation has focused on its efficacy in reducing abdominal pain and improving stool consistency in IBS-D patients.

Brand names
Chang-Ji-AnChangji'an capsule
Other names
Changji'an CapsuleChangji'an Jiaonang
02

Targets

NTRK1 (Tropomyosin-related receptor kinase A)NGF (Nerve growth factor)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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