Children's PediaCare Multi-Symptom Cold

Children's PediaCare Multi-Symptom Cold is an over-the-counter (OTC) combination medication designed for the temporary relief of symptoms associated with the common cold, flu, and upper respiratory allergies in children aged 4 to 11. The formulation typically includes four active ingredients: acetaminophen (a pain reliever and fever reducer), chlorpheniramine maleate (an antihistamine), dextromethorphan hydrobromide (a cough suppressant), and phenylephrine hydrochloride (a nasal decongestant). Acetaminophen works by inhibiting prostaglandin synthesis in the central nervous system; chlorpheniramine blocks H1 histamine receptors; dextromethorphan acts on the cough center in the medulla to elevate the cough threshold; and phenylephrine is an alpha-1 adrenergic agonist that causes vasoconstriction in the nasal mucosa. While the brand name has been reported as discontinued in the U.S. by some sources, various formulations under the PediaCare umbrella have historically been manufactured and distributed by companies such as Strides Pharma and Fareva Richmond.

Brand names

Children's PediaCare Multi-Symptom ColdPediaCare Multi-Symptom Cold