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Children's Acetaminophen + Amantadine Granules
- Development stage
- Unknown
- Lead developer
- Shenyang Dongxing Pharmaceutical Technology
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Children's Acetaminophen + Amantadine Granules (小儿氨酚烷胺颗粒) is a pediatric combination small-molecule product developed and manufactured by Shenyang Dongxing Pharmaceutical Technology. It is indicated for the symptomatic relief of the common cold and influenza in children. The formulation combines acetaminophen, which exerts analgesic and antipyretic effects through the inhibition of cyclooxygenase (COX) enzymes and central analgesic pathways, with amantadine, which historically provides antiviral activity against Influenza A by blocking the M2 ion channel and possesses secondary CNS effects via NMDA receptor modulation. The product is administered orally as granules and is currently approved for use in China.
- Brand names
- 小儿氨酚烷胺颗粒
- Other names
- 氨酚烷胺Acetaminophen + Amantadine
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)CHRM2 (M2)COXSLC7A11 (Cystine-Glutamate Antiporter)
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