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chlorhexidine + lidocaine
- Development stage
- Phase 3
- Lead developer
- Sandoz
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Angal S is a fixed-dose combination topical spray containing the antiseptic chlorhexidine gluconate and the local anesthetic lidocaine hydrochloride. Developed by Sandoz (Lek), it is used for the symptomatic treatment of inflammatory and infectious diseases of the oral cavity and pharynx, such as sore throat, pharyngitis, and gingivitis. Chlorhexidine provides broad-spectrum antimicrobial activity by disrupting bacterial and fungal cell membranes, while lidocaine acts as a sodium channel blocker to provide rapid, localized pain relief. The 'S' in the name typically denotes the spray formulation, and variants may include flavoring agents such as menthol or lemon.
- Brand names
- Angal SAngalAngal MentholAngal Lemon
- Other names
- chlorhexidine gluconate + lidocaine hydrochloride
02
Targets
NaV (Voltage-gated sodium channels)
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