Drug intelligence / Profile preview

chlorhexidine + lidocaine (Pharmedic)

Development stage
Unknown
Lead developer
Pharmedic
Modality
Small Molecules
Administration
Buccal, Topical
01

Overview

Orafar is a combination antiseptic and local anesthetic product developed and marketed by Pharmedic. It contains chlorhexidine gluconate, a biguanide antiseptic with broad-spectrum antimicrobial activity, and lidocaine hydrochloride, an amide-type local anesthetic. The product is designed for the local treatment of infections and inflammatory conditions of the oral cavity and pharynx, such as sore throat, gingivitis, and mouth ulcers. Chlorhexidine acts by disrupting microbial cell membranes, while lidocaine provides rapid pain relief by blocking voltage-gated sodium channels. Orafar is available in dosage forms including lozenges and sprays for topical application to the oral mucosa.

Brand names
Orafar
Other names
chlorhexidine gluconate + lidocaine hydrochloride
02

Targets

NaV (Voltage-gated sodium channels)

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