Drug intelligence / Profile preview

chlorpheniramine + midazolam

Development stage
Unknown
Lead developer
Merck
Modality
Small Molecules
Administration
Intranasal, Intravenous, Intradermal
01

Overview

This represents a drug interaction rather than an intentional combination product. Chlorpheniramine is a histamine H1 receptor antagonist used for allergic conditions, while midazolam is a benzodiazepine used for sedation, anxiolysis, and seizure management. When used together, these medications can increase the risk of CNS depression and sedation.

02

Targets

HRH1 (Histamine H1 Receptor)

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