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Drug intelligence / Profile preview
chlorpheniramine + paracetamol + phenylephrine (Kylon Remedies)
- Development stage
- Phase 3
- Lead developer
- Kylon Remedies
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
KYLCOLD is a pediatric oral suspension developed by Kylon Remedies for the symptomatic relief of the common cold, fever, nasal congestion, and minor body aches in children. It is a fixed-dose combination containing three active ingredients: paracetamol (acetaminophen), phenylephrine, and chlorpheniramine. Paracetamol acts as an analgesic and antipyretic by inhibiting prostaglandin synthesis in the central nervous system. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that functions as a nasal decongestant by constricting blood vessels in the nasal passages. Chlorpheniramine is a first-generation antihistamine that competitively blocks histamine H1 receptors to alleviate symptoms such as sneezing, rhinorrhea, and watery eyes.
- Brand names
- KYLCOLD
- Other names
- chlorpheniramine maleate + paracetamol + phenylephrine hydrochloride
02
Targets
mAChR (Muscarinic acetylcholine receptors)ADRA1A (α1A)COXHRH1 (Histamine H1 Receptor)
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