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Vitamin D3 + Vitamin K-Nupathways is a high-potency dietary supplement combination featuring cholecalciferol (Vitamin D3) and Vitamin K, developed by Metagenics in partnership with Nupathways. Vitamin D3 functions as a steroid hormone precursor that binds to the Vitamin D receptor (VDR), promoting intestinal calcium absorption and maintaining serum calcium and phosphate concentrations for bone mineralization. Vitamin K, typically provided in its K1 and K2 (menaquinone-7) forms, acts as an essential cofactor for the enzyme gamma-glutamyl carboxylase, which activates proteins like osteocalcin for bone formation and matrix Gla protein (MGP) to prevent vascular calcification. This combination is designed to support bone density, cardiovascular health, and immune system regulation by ensuring proper calcium utilization within the body.
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