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Drug intelligence / Profile preview
choline + zolpidem
- Development stage
- Unknown
- Lead developer
- Sanofi
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Choline + zolpidem appears to denote a **combination product or co-administration concept** involving choline and zolpidem for insomnia, rather than a well-established, uniquely identified approved pharmaceutical product. In the provided context, the only clearly supported active pharmaceutical ingredient is **zolpidem**, a nonbenzodiazepine sedative-hypnotic that acts as a positive allosteric modulator at the benzodiazepine site of the **gamma-aminobutyric acid type A receptor**, with relative selectivity for receptor complexes containing the alpha1 subunit, thereby promoting sleep initiation. Choline is a nutritional compound and precursor for phosphatidylcholine and acetylcholine, but no specific validated therapeutic insomnia mechanism or distinct marketed fixed-dose drug identity for the exact combination was established from the supplied material.
- Brand names
- Sentrazolpidem PM-5Gabazolpidem-5Gabazolpidem5Gabazolpidem 5
- Other names
- choline + zolpidem
02
Targets
GABRR (GABA-A receptor subunit rho)GABA-B (Gamma-aminobutyric acid receptor type B)GABRA1 (Gamma-aminobutyric acid type A receptor alpha 1 subunit)
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