Drug intelligence / Profile preview

chromium (51Cr) edetate

Development stage
Unknown
Lead developer
Marnel Pharmaceuticals
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Chromium Cr-51 EDTA is a small-molecule radiopharmaceutical diagnostic agent used primarily for the estimation of glomerular filtration rate (GFR). It consists of the radioactive isotope chromium-51 complexed with the chelating agent ethylenediamine tetraacetic acid (EDTA). Following intravenous administration, the complex is almost exclusively cleared from the plasma by glomerular filtration, with negligible tubular secretion or reabsorption and minimal binding to plasma proteins. These pharmacokinetic properties make it an ideal marker for the precise assessment of renal function. It is also utilized in research settings for intestinal permeability studies and plasma clearance investigations.

Brand names
BACMIN
Other names
Chromium Cr-51 EDTAChromium Cr-51 EdetateCr-51-ethylenediamine tetraacetic acidCr51-ethylenediamine tetraacetic acidCr 51-ethylenediamine tetraacetic acidChromium-51-EDTAChromium51-EDTAChromium 51-EDTA

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