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ciclosporin + dexamethasone
- Development stage
- Unknown
- Lead developer
- Novartis
- Modality
- Small Molecules
- Administration
- Intravitreal
01
Overview
A combination of two immunosuppressive drugs that work synergistically to inhibit T cell activation and inflammatory responses. Ciclosporin is a calcineurin inhibitor that prevents T cell activation by inhibiting the production of cytokines like IL-2, while dexamethasone is a potent synthetic glucocorticoid with anti-inflammatory properties.
- Other names
- cyclosporine + dexamethasone
02
Targets
PPIA (Peptidyl-prolyl cis-trans isomerase A)GR (Glucocorticoid receptor)CN (Calcineurin)
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