Drug intelligence / Profile preview

CIGB-210 (Center for Genetic Engineering and Biotechnology)

Development stage
Unknown
Lead developer
Center for Genetic Engineering and Biotechnology
Modality
Recombinant Proteins and Enzymes
Administration
Intranasal, Inhalation
01

Overview

CIGB-210 is a recombinant protein therapeutic developed by the Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba. Originally investigated for the treatment of cystic fibrosis, it has been repurposed as a potential therapy for COVID-19. The drug is designed to inhibit the entry of the SARS-CoV-2 virus into host cells by acting as a soluble decoy or by interfering with the interaction between the viral spike protein and the host cell receptors. Clinical development in Cuba has progressed to Phase 2 trials to evaluate its safety and efficacy in patients with COVID-19.

Other names
keratin 10-derived peptidekeratin10-derived peptidekeratin-10-derived peptide
02

Targets

VIM (Vimentin)

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