cilazapril + hydrochlorothiazide

Cilazapril + hydrochlorothiazide is a fixed-dose combination medication used to treat mild-to-moderate essential hypertension in patients for whom dual therapy is appropriate. It contains two active ingredients: - **Cilazapril** is an angiotensin-converting enzyme (ACE) inhibitor that works by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. - **Hydrochlorothiazide** is a thiazide diuretic that reduces blood pressure by increasing the excretion of sodium and water from the kidneys, thereby decreasing blood volume. This combination is typically prescribed when monotherapy with either agent does not adequately control blood pressure. It should not be used as initial therapy; patients are usually titrated on each component separately before switching to the fixed-dose combination[1][4][10]. The product has been marketed under several brand names and was previously supplied in countries such as Canada and New Zealand[3][7][8].

Brand names

Apo-Cilazapril/HCTZInhibace PlusTEVA-Cilazapril/HCTZ

Other names

cilazapril and hydrochlorothiazide