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cimetidine + diphenhydramine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral, Intravenous, Intramuscular
01
Overview
A combination of cimetidine, a histamine H2-receptor antagonist used to reduce gastric acid secretion, and diphenhydramine, a first-generation H1-receptor antihistamine with sedative properties. Cimetidine works by blocking H2 receptors on gastric parietal cells, while diphenhydramine competes with histamine for H1 receptor sites on effector cells.
02
Targets
HRH1 (Histamine H1 Receptor)HRH2 (Histamine H2 Receptor)
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