Drug intelligence / Profile preview

ciprofloxacin + dexamethasone

Development stage
Phase 3
Lead developer
Alcon
Modality
Small Molecules
Administration
Otic
01

Overview

**Ciprofloxacin + dexamethasone** is a fixed-dose antibacterial and corticosteroid combination, most prominently supplied as an otic suspension containing ciprofloxacin 0.3% and dexamethasone 0.1%. Ciprofloxacin is a fluoroquinolone antibacterial that inhibits bacterial type II topoisomerases, while dexamethasone is a glucocorticoid that suppresses local inflammation. In the United States, the otic product is approved for acute otitis externa in patients aged 6 months and older and for acute otitis media in pediatric patients with tympanostomy tubes. ([accessdata.fda.gov](https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021537s017lbl.pdf))

Brand names
CiprodexKombinil-Duo
Other names
ciprofloxacin and dexamethasoneciprofloxacin/dexamethasonedexamethasone + ciprofloxacin
02

Targets

GR (Glucocorticoid receptor)Neuraminidase

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