Drug intelligence / Profile preview

cisatracurium + neostigmine

Development stage
Phase 4
Lead developer
Organon
Modality
Small Molecules
Administration
Intravenous
01

Overview

A combination of cisatracurium, a non-depolarizing neuromuscular blocking agent, and neostigmine, a cholinesterase inhibitor used to reverse the neuromuscular blockade induced by cisatracurium. This combination is commonly used in anesthesia practice, where cisatracurium facilitates tracheal intubation and provides skeletal muscle relaxation during surgery, while neostigmine is administered afterward to antagonize the neuromuscular blocking effects and restore normal muscle function.

02

Targets

AcetylcholinesteraseMuscle-type nicotinic acetylcholine receptor

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