Drug intelligence / Profile preview

cisplatin + cyclophosphamide + doxorubicin + etoposide

Development stage
Unknown
Lead developer
Michigan State University
Modality
Small Molecules
Administration
Intravenous
01

Overview

A combination chemotherapy regimen consisting of cisplatin, cyclophosphamide, doxorubicin, and etoposide. This regimen has been studied primarily in the treatment of small cell lung cancer (SCLC). The combination was designed to potentially enhance efficacy through synergistic interactions between the component drugs, but studies showed significant toxicity concerns.

Other names
PCDE
02

Targets

TOP2A (DNA topoisomerase II)DNA

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