cisplatin + docetaxel + gefitinib + pemetrexed + vinorelbine + gemcitabine

This is a combination of six anticancer drugs that have been studied in various combinations, but not as a single six-drug regimen based on available information. The individual components have different mechanisms of action: - Cisplatin: A platinum-based chemotherapy that causes DNA crosslinking - Docetaxel: A taxane that inhibits cell division by disrupting microtubule function - Gefitinib: An EGFR tyrosine kinase inhibitor - Pemetrexed: An antifolate that inhibits multiple enzymes in the folate pathway - Vinorelbine: A vinca alkaloid that disrupts microtubules - Gemcitabine: A nucleoside analog that inhibits DNA synthesis Various combinations of these drugs have been studied for the treatment of non-small-cell lung cancer (NSCLC) and other cancers.