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This is a combination therapy regimen consisting of cisplatin (a platinum-based chemotherapy agent), docetaxel (a taxane chemotherapy agent), and sintilimab (an immune checkpoint inhibitor). The combination is being studied for the treatment of advanced cancers, including gastric cancer and non-small cell lung cancer (NSCLC). Sintilimab is a recombinant fully human immunoglobulin G4 monoclonal antibody that blocks the interaction between PD-1 and PD-L1, while cisplatin and docetaxel are cytotoxic chemotherapy agents.
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