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cisplatin + gemcitabine + ifosfamide
- Development stage
- Unknown
- Lead developer
- Michigan State University
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
A chemotherapy combination regimen consisting of cisplatin, gemcitabine, and ifosfamide. This triplet regimen is primarily used as salvage therapy for patients with relapsed or refractory cancers, particularly germ-cell tumors, urothelial carcinoma, and ovarian cancer. The regimen typically includes gemcitabine 1000 mg/m² on days 1 and 5, ifosfamide 1200 mg/m²/day on days 1-5, and cisplatin 20 mg/m²/day on days 1-5, with G-CSF support, repeated every 3 weeks.
- Other names
- GIP regimen
02
Targets
DNA polymerase familyDNARNR (Ribonucleotide reductase)
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