Drug intelligence / Profile preview

citalopram + clopidogrel

Development stage
Unknown
Lead developer
Lundbeck
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination of two pharmaceutical drugs: citalopram, a selective serotonin reuptake inhibitor (SSRI) antidepressant, and clopidogrel, an antiplatelet agent. Citalopram increases serotonin levels in the brain by inhibiting its reuptake into presynaptic cells, primarily used for treating depression and anxiety disorders. Clopidogrel is a P2Y12 adenosine diphosphate (ADP) receptor antagonist that inhibits platelet aggregation to reduce the risk of cardiovascular events such as heart attack and stroke. The combination may be prescribed in patients with coexisting depression and cardiovascular disease but requires careful monitoring due to increased bleeding risk[2][4][5][9].

Brand names
Celexa + Plavix
Other names
citalopram + PlavixCelexa + clopidogrel
02

Targets

SERT (Sodium-dependent serotonin transporter)P2Y12 (Purinergic P2Y12 receptor)

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