Drug intelligence / Profile preview

citric acid + L-ascorbic acid

Development stage
Unknown
Lead developer
Verma Drugs
Modality
Small Molecules
Administration
Parenteral
01

Overview

citric acid + L-ascorbic acid (marketed under the brand name CitraVit by Verma Drugs) is a specialized acidic citrate dialysis solution enhanced with L-ascorbic acid (Vitamin C) used for patients with end-stage renal disease (ESRD) undergoing hemodialysis. Citric acid acts as a local anticoagulant by chelating calcium ions, which significantly reduces the requirement for heparin during dialysis sessions and minimizes the risk of thrombosis. L-ascorbic acid serves as a potent antioxidant that mitigates oxidative stress and inflammation associated with hemodialysis. Additionally, L-ascorbic acid improves the management of renal anemia by enhancing iron mobilization and absorption, thereby reducing the need for monthly iron administration and stabilizing hemoglobin levels.

Brand names
CitraVit
Other names
CD solution with Vitamin-Ccitrate + L-ascorbic acidcitrate + vitamin Ccitric acid + vitamin Ccitric acid solution with L-ascorbic acidcitric acid solution with vitamin C

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