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citric acid + potassium citrate + sodium citrate
- Development stage
- Unknown
- Lead developer
- Westminster Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Citric acid + potassium citrate + sodium citrate is a systemic urinary alkalizing agent composed of citric acid and its potassium and sodium salts. It is primarily indicated for the treatment of metabolic acidosis and the management of kidney stones (specifically calcium oxalate and uric acid stones) associated with hypocitraturia. Upon oral administration, the citrate salts are metabolized to bicarbonate, which increases systemic and urinary pH. This alkalinization helps dissolve uric acid stones and prevents the crystallization of calcium salts. Additionally, increased urinary citrate levels form chemical complexes with calcium, reducing the concentration of free calcium available for stone formation. The drug is also used as an adjuvant in gout therapy to facilitate the excretion of uric acid. It is commonly available as an oral liquid solution.
- Brand names
- TricitratesPolycitraPolycitra-LCCytra-3Cytra3Cytra 3
- Other names
- citric acid + potassium-sodium citratecitric acid/potassium citrate/sodium citrate
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