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CKD-314 (Nafabelltan) is a small molecule drug developed by Chong Kun Dang Pharmaceutical. It has been investigated as an intravenous treatment for hospitalized adult patients diagnosed with COVID-19 pneumonia. In clinical trials, the combination "CKD-314 + SOC" refers to the administration of CKD-314 alongside standard of care treatments for COVID-19 pneumonia. The mechanism of action involves inhibition of serine proteases (SP inhibitor), which may modulate inflammatory and coagulation pathways relevant to severe viral infections[10][8][1]. The primary indication in clinical studies has been COVID-19 pneumonia.
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