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CKD-378 + D745 is an investigational oral combination therapy under development by Chong Kun Dang Pharmaceutical for the treatment of type 2 diabetes mellitus. Both components are small molecule drugs. Clinical trials have focused on evaluating the pharmacokinetics, safety, and potential drug-drug interactions when these agents are administered together in healthy adults. The mechanism of action and specific targets for each component have not been publicly disclosed as of June 2025. The combination is being studied primarily for its effects on metabolic parameters relevant to diabetes management[1][2][3][5][6].
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