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clobetasol propionate + mucopolysaccharide polysulfate

Development stage
Preclinical
Lead developer
Formosa Pharmaceuticals
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

A combination therapy consisting of clobetasol propionate, a super-high potency topical corticosteroid, and mucopolysaccharide polysulfate (MPS), a moisturizing ingredient. Studies have shown that MPS can improve tight junction barrier impairment induced by clobetasol propionate. This combination may help delay relapses in atopic dermatitis by maintaining skin barrier function while providing anti-inflammatory effects. Clobetasol propionate works by activating natural substances in the skin to reduce swelling, redness, and itching, while MPS appears to protect the tight junction barrier function in the skin.

Other names
clobetasol 17-propionate + mucopolysaccharide polysulfate
02

Targets

GR (Glucocorticoid receptor)

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