Drug intelligence / Profile preview

clobetasone butyrate + gentamicin sulfate + miconazole nitrate

Development stage
Unknown
Lead developer
Octave Life Sciences
Modality
Small Molecules
Administration
Topical
01

Overview

Dermisytic is a topical combination cream containing clobetasone butyrate, gentamicin sulfate, and miconazole nitrate. It is marketed by Octave Life Sciences for the treatment of inflammatory skin conditions complicated by bacterial or fungal infections. Clobetasone butyrate is a corticosteroid that reduces inflammation, redness, and itching. Gentamicin sulfate is an aminoglycoside antibiotic that targets bacterial infections by inhibiting protein synthesis. Miconazole nitrate is an imidazole antifungal that disrupts fungal cell membrane synthesis. Together, these components provide comprehensive relief from skin infections and associated inflammation.

Brand names
DermisyticDermisytic Cream
Other names
clobetasone + gentamicin + miconazoleclobetasone butyrate + gentamicin sulfate + miconazole nitrateclobetasone butyrate, gentamicin sulfate and miconazole nitrate cream
02

Targets

Bacterial RibosomeGR (Glucocorticoid receptor)CYP51A1 (Sterol 14α-demethylase)MR (Mineralocorticoid receptor)

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