Drug intelligence / Profile preview

clonazepam + tianeptine

Development stage
Unknown
Lead developer
Roche
Modality
Small Molecules
Administration
Oral
01

Overview

A combination of clonazepam, a benzodiazepine with anxiolytic and anticonvulsant properties, and tianeptine, an atypical tricyclic antidepressant with mu-opioid receptor agonist activity. This combination may be used for treating comorbid depression and anxiety disorders. The combination increases the risk of sedation and requires careful monitoring.

02

Targets

DOR (Opioid Receptor Delta 1)GABRR (GABA-A receptor subunit rho)GluR (Glutamate receptors)MOR (Mu opioid receptor)

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