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clonazepam + trihexyphenidyl

Development stage: Unknown
Lead developer: Roche
Modality: Small Molecules
Administration: Oral

Overview

A combination medication consisting of clonazepam (a benzodiazepine) and trihexyphenidyl (an anticholinergic agent). This combination is primarily used for treating dystonia, particularly in children with cerebral palsy. Clinical trials have shown that this combination is more effective than trihexyphenidyl alone in reducing dystonia severity, improving upper limb function, reducing pain, and enhancing quality of life.

Targets

GABRR (GABA-A receptor subunit rho)mAChR (Muscarinic acetylcholine receptors)

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