clotrimazole + beclomethasone

Clotrimazole + beclomethasone is a topical combination therapy developed by Biogracea Medicare, primarily indicated for the treatment of fungal skin infections associated with inflammatory symptoms. Clotrimazole is a synthetic imidazole antifungal agent that exerts its effect by inhibiting the enzyme lanosterol 14-alpha demethylase, thereby disrupting the biosynthesis of ergosterol, a critical component of the fungal cell membrane. Beclomethasone dipropionate is a potent corticosteroid that acts as a glucocorticoid receptor agonist, providing anti-inflammatory, antipruritic, and vasoconstrictive actions to alleviate redness, swelling, and itching. This combination is particularly effective for conditions like tinea pedis, tinea cruris, and cutaneous candidiasis where secondary inflammation is present.

Brand names

GRACE-B

Other names

clotrimazole and beclomethasone dipropionate