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clotrimazole + lactobacillus
- Development stage
- Unknown
- Lead developer
- Bennet Pharmaceuticals
- Modality
- Small Molecules, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Vaginal
01
Overview
Clotrimazole + lactobacillus is a combination medication primarily used to treat vaginal infections, particularly vulvovaginal candidiasis (VVC). This combination leverages the antifungal properties of clotrimazole with the probiotic benefits of lactobacillus. Clotrimazole works by preventing the formation of the fungal protective covering, thereby stopping fungal growth. Lactobacillus acts as a probiotic that helps maintain vaginal health by producing anti-infectious substances and restoring the vaginal microecology. Clinical studies have shown that this combination may improve treatment outcomes for uncomplicated VVC compared to clotrimazole alone, with higher cure rates and better restoration of vaginal flora.
- Brand names
- KlovinalClid VLCliza VLCloclinda-VTVagi VL
- Other names
- Clotrimazole Vaginal Tablets plus probiotic Lacidophilin Vaginal CapsulesLactobacillus Combination
02
Targets
CYP51A1 (Sterol 14α-demethylase)
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