Drug intelligence / Profile preview

coal tar + coconut oil + salicylic acid

Development stage
Unknown
Lead developer
St Thomas' Hospital
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

This is a topical combination drug containing coal tar, coconut oil, and salicylic acid. It is primarily used for the treatment of hyperkeratotic and scaling skin conditions such as scalp psoriasis, seborrheic dermatitis (including dandruff), and atopic dermatitis involving the scalp[1][5][8]. \n- **Coal tar** acts as an antipruritic (relieves itching), keratoplastic (normalizes skin cell growth), and has weak antiseptic properties. It helps reduce inflammation and scaling by slowing down excessive skin cell proliferation[1][6]. \n- **Salicylic acid** is a keratolytic agent that softens and removes scales by promoting desquamation of corneocytes (outermost skin cells)[2][6]. This enhances penetration of other topical treatments. \n- **Coconut oil** serves as an emollient base that moisturizes the scalp/skin, helping to reduce dryness and irritation while aiding in delivery of active ingredients[5]. \n\nThe combination may be found in ointments or lotions under various brand names. These products are available over-the-counter or by prescription depending on jurisdiction.

Brand names
CapasalCocoisSebcoCoco-Scalp
Other names
coconut oil compound ointment
02

Targets

Stratum corneum intercellular lipids and corneocyte adhesion structures

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