Drug intelligence / Profile preview

coal tar + triamcinolone acetonide

Development stage
Unknown
Modality
Small Molecules
Administration
Topical
01

Overview

Coal tar + triamcinolone acetonide is a topical medication that combines the keratoplastic properties of coal tar with the anti-inflammatory effects of triamcinolone acetonide (a corticosteroid). This combination is used to treat various dermatological conditions including psoriasis, eczema, dermatitis, and lichen planus. Coal tar helps slow rapid skin cell turnover and reduce inflammation, while triamcinolone acetonide provides additional anti-inflammatory effects. The combination appears to have synergistic effects, allowing for reduced corticosteroid concentration and minimizing potential side effects.

02

Targets

GR (Glucocorticoid receptor)AHR (Aryl hydrocarbon receptor)

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