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codeine + paracetamol
- Development stage
- Unknown
- Lead developer
- Quest Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Codopar is a branded generic combination analgesic containing codeine phosphate and paracetamol (acetaminophen). It is manufactured by Quest Pharmaceuticals in Nepal for the management of mild to moderate pain. Paracetamol provides analgesic and antipyretic effects, likely through the inhibition of prostaglandin synthesis in the central nervous system. Codeine is an opioid analgesic that acts as a mu-opioid receptor agonist after being metabolized to morphine, altering the perception of pain. This combination is typically used when single-ingredient analgesics are insufficient for pain control.
- Brand names
- Codopar
- Other names
- CodoparCodeine plus Paracetamolco-codamol
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)MOR (Mu opioid receptor)PGHS-1 (Prostaglandin G/H Synthase 1)
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