Drug intelligence / Profile preview

codeine + platycodon

Development stage
Unknown
Lead developer
Nichi-Iko Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Codeine + platycodon is a combination drug consisting of codeine, an opioid analgesic and antitussive, and platycodon (typically as Platycodon grandiflorus extract), a traditional herbal expectorant. This combination is primarily used for the symptomatic treatment of cough and difficult sputum expectoration in conditions such as upper respiratory tract inflammation and acute bronchitis. Codeine acts mainly by binding to mu-opioid receptors in the central nervous system to suppress cough reflexes and relieve mild to moderate pain. Platycodon is believed to exert its effects by promoting mucus secretion, facilitating sputum expulsion, and possibly providing anti-inflammatory benefits[4][1]. The combination leverages both the central antitussive action of codeine and the peripheral expectorant effect of platycodon.

Other names
Opisezol Codeine Solution
02

Targets

MOR (Mu opioid receptor)

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