codeine phosphate + pseudoephedrine hydrochloride + triprolidine

Codeine phosphate + pseudoephedrine hydrochloride + triprolidine is an oral small-molecule combination cough and cold product used for the temporary relief of cough and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold. The combination contains **codeine phosphate**, an opioid antitussive that suppresses coughing primarily through central agonism at opioid receptors in the medullary cough center; **pseudoephedrine hydrochloride**, an indirect sympathomimetic decongestant that promotes norepinephrine release and reduces nasal congestion through adrenergic vasoconstrictive effects; and **triprolidine**, a first-generation H1 antihistamine that counters histamine-mediated allergic symptoms. It has been marketed under brand names including **Triacin-C** and **Pseudodine C**, typically as an oral syrup formulation.

Brand names

Triacin-CPseudodine C

Other names

codeine phosphate + pseudoephedrine hydrochloride + triprolidine hydrochloride