Drug intelligence / Profile preview

coenzyme Q10 + dehydroepiandrosterone + vitamin E + vitamin C + omega-3 fatty acids

Development stage
Unknown
Lead developer
Theralogix
Modality
Small Molecules
Administration
Oral
01

Overview

This combination is a multi-ingredient nutraceutical stack primarily utilized in reproductive medicine to improve oocyte quality and ovarian response, particularly in women with diminished ovarian reserve (DOR) or advanced maternal age undergoing assisted reproductive technologies (ART). Coenzyme Q10 (CoQ10) supports mitochondrial function and ATP production within the oocyte, which is critical for spindle assembly and chromosomal segregation. Dehydroepiandrosterone (DHEA) serves as a precursor for follicular steroidogenesis, potentially increasing the number of recruitable follicles and improving the microenvironment of the developing egg. Vitamins C and E act as synergistic antioxidants to mitigate oxidative stress in the follicular fluid, protecting oocytes from reactive oxygen species (ROS). Omega-3 fatty acids (EPA and DHA) provide anti-inflammatory effects, support cellular membrane integrity, and may enhance uterine blood flow. While not a single FDA-approved drug product, this specific combination is frequently studied and recommended by fertility specialists to optimize IVF outcomes.

Other names
DHEA/CoQ10/VitE/VitC/Omega-3 stackFertility antioxidant cocktailCCRM fertility supplement protocol
02

Targets

PPARA (Peroxisome proliferator-activated receptor alpha)PPARG (Peroxisome proliferator-activated receptor gamma)Mitochondrial respiratory complex I ubiquinone-binding channelESR2 (ERβ)ESR1 (ERα)AR (Adrenergic receptors)

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