compound glycyrrhizin (Kawin Biosciences)

Kaiyin Ganle is a brand of Compound Glycyrrhizin Capsules developed and marketed by Kawin Biosciences. It is a combination product containing glycyrrhizin (glycyrrhizic acid), glycine, and DL-methionine. The drug is primarily used in China for the treatment of chronic liver diseases and to improve abnormal liver function. It also possesses anti-inflammatory and immunomodulatory properties, leading to its use in dermatological conditions such as eczema, dermatitis, and alopecia areata. The mechanism of action involves the inhibition of 11β-hydroxysteroid dehydrogenase, which prevents the breakdown of cortisol, and the inhibition of HMGB1, a pro-inflammatory cytokine mediator. The inclusion of glycine and methionine helps to mitigate the mineralocorticoid-like side effects typically associated with high-dose glycyrrhizin.

Brand names

Kaiyin Ganle凯因甘乐

Other names

Compound Glycyrrhizin Capsules复方甘草酸苷胶囊