Drug intelligence / Profile preview

corticosteroid + normal saline

Development stage
Unknown
Modality
Small Molecules
Administration
Intraarticular, Intralesional, Intranasal, Local Injection
01

Overview

A combination of a corticosteroid (a class of anti-inflammatory drugs) and normal saline (0.9% sodium chloride solution). This mixture is not a single branded or proprietary product but rather a compounded preparation used in various clinical settings. Corticosteroids act by suppressing inflammation and modulating immune responses through glucocorticoid receptor activation, while normal saline serves as an isotonic diluent or vehicle for drug delivery. The combination is commonly used for local injections (e.g., intra-articular, intralesional), nasal irrigations in chronic sinusitis, or as part of other procedures where dilution or volume expansion is needed[2][6]. The specific corticosteroid used can vary (e.g., triamcinolone acetonide, methylprednisolone), depending on the indication.

Other names
corticosteroid and normal salinesteroid + salinesteroid-saline combination
02

Targets

GR (Glucocorticoid receptor)SERPINA6 (Corticosteroid-binding globulin)MR (Mineralocorticoid receptor)

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