corticosteroid + saline + local anesthetic

A combination of a corticosteroid, saline, and a local anesthetic is commonly used in clinical practice for the diagnosis and treatment of musculoskeletal pain, inflammation, and certain chronic pain conditions. The corticosteroid component provides anti-inflammatory effects by suppressing immune responses and reducing cytokine production. The local anesthetic offers immediate pain relief by blocking sodium channels in nerve fibers to inhibit nerve signal transmission. Saline acts as a diluent or vehicle for injection. This combination is typically administered via intra-articular, epidural, or soft tissue injections for conditions such as arthritis, bursitis, tendinopathies, spinal pain syndromes (including disc herniation), and periarticular inflammation[1][2][6][7]. Commonly used corticosteroids include triamcinolone and methylprednisolone; lidocaine is the most frequently used local anesthetic[1]. The mixture can be tailored based on patient needs and site of injection.

Other names

steroids + local anesthetics