CPT-11 + raltegravir + midazolam

This is a combination regimen consisting of three distinct drugs: - **Irinotecan (CPT-11)** is a topoisomerase I inhibitor used primarily as an antineoplastic agent in the treatment of metastatic colorectal and pancreatic cancers. It works by inhibiting DNA topoisomerase I, leading to DNA damage and cell death[1][2][3][4]. - **Raltegravir** is an antiretroviral medication classified as an HIV integrase strand transfer inhibitor. It blocks the integration of viral DNA into the host genome and is used in combination therapy for HIV/AIDS[6][9]. - **Midazolam** is a benzodiazepine with sedative, anxiolytic, amnestic, and anticonvulsant properties. It acts as a positive allosteric modulator at GABA-A receptors and is commonly used for procedural sedation or preoperative anxiolysis[7][10]. There are no known approved fixed-dose combinations or unique brand names for this specific triple-drug regimen; it represents a co-administration protocol rather than a single pharmaceutical product.

Brand names

Camptosar

Other names

irinotecan + raltegravir + midazolam