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curcumin + diclofenac sodium
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of curcumin, an active component of turmeric with anti-inflammatory and antioxidant properties, and diclofenac sodium, a non-steroidal anti-inflammatory drug (NSAID). This combination has been studied for its potential synergistic effects in treating inflammatory conditions, particularly rheumatoid arthritis. Research suggests that curcumin may enhance the therapeutic efficacy of diclofenac while potentially reducing its side effects and required dosage.
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)PGHS-1 (Prostaglandin G/H Synthase 1)IL1B (Interleukin-1 beta)
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