Drug intelligence / Profile preview

curcumin + huperzine A

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

A combination supplement containing curcumin (the primary polyphenolic compound from turmeric) and huperzine A (an alkaloid extracted from Huperzia serrata). This combination has been studied in patients with dementia, including Alzheimer’s disease, dementia with Lewy bodies, and mild cognitive impairment. The supplement is thought to improve cognitive function through multiple mechanisms. Curcumin exhibits anti-inflammatory, antioxidant, and chemoprotective properties[3]. Huperzine A acts as a potent cholinesterase inhibitor and glutamic acid receptor antagonist[1][2][4]. Clinical studies have shown significant improvements in cognitive function scores at 6–12 weeks and 22–28 weeks compared to baseline in open-label trials[1][2].

Other names
huperzine A and curcumincurcumin and huperzine A
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)Acetylcholinesterase

Beyond the preview

Go deeper on curcumin + huperzine A.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on curcumin + huperzine A.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call