Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Cymirafen (UCSD Moores Cancer Center)
- Development stage
- Unknown
- Lead developer
- UC San Diego Moores Cancer Center
01
Overview
Cymirafen (UCSD Moores Cancer Center): sourced facts only. name: "Cymirafen binds to human and cynomolgus LGR5 with Kd of 0.27 and 0.38 nM, respectively." [DOI:10.1158/1538-7445.am2025-1806]; target: "Cymirafen binds to human and cynomolgus LGR5 with Kd of 0.27 and 0.38 nM, respectively." [DOI:10.1158/1538-7445.am2025-1806]; developer: "UCSD Moores Cancer Center, La Jolla, CA." [DOI:10.1158/1538-7445.am2025-1806]; modality: "Cymirafen: A protein-drug conjugate that target LGR4/LGR5/LGR6-positive cancer stem cells" [DOI:10.1158/1538-7445.am2025-1806]; stage: "On a dose schedule of 85 mg/kg q7dx4, cymirafen was well tolerated in mice and active in CDX models of multiple types of cancer (colon, gastric, ovarian, neuroblastoma)." [DOI:10.1158/1538-7445.am2025-1806]
02
Targets
LGR5 (Leucine-rich repeat-containing G-protein coupled receptor 5)
Beyond the preview
Go deeper on Cymirafen (UCSD Moores Cancer Center).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Cymirafen (UCSD Moores Cancer Center).