Drug intelligence / Profile preview

cyproheptadine + tricholine citrate

Development stage
Unknown
Lead developer
Chemross Lifesciences
Modality
Small Molecules
Administration
Oral
01

Overview

Camalerg is a branded generic combination medication developed and marketed by Chemross Lifesciences, typically formulated as an oral syrup. It contains cyproheptadine hydrochloride, a first-generation antihistamine and serotonin antagonist, and tricholine citrate, a lipotropic agent. Cyproheptadine functions by antagonizing histamine H1 receptors and serotonin receptors, particularly in the hypothalamus, which results in increased appetite and relief from allergic symptoms. Tricholine citrate acts as a precursor to choline, aiding in the mobilization of liver fat and supporting hepatic function. Camalerg is primarily indicated for the treatment of appetite loss, weight loss, and allergic conditions such as rhinitis, urticaria, and pruritus.

Brand names
Camalerg
Other names
Camalerg 200ml SypCamalerg200ml SypCamalerg-200ml Syp
02

Targets

mAChR (Muscarinic acetylcholine receptors)5-HT2 (5-HT2 receptor family)AR (Adrenergic receptors)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))HRH1 (Histamine H1 Receptor)SIGMAR1 (Sigma non-opioid intracellular receptor 1)DRD (Dopamine receptors)

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